CAN:s bibliotek

*000      am
*00119785
*008070120|1989|||||||||||e|m||||||||0|eng|d
*020  $a91-7900-794-5$x91-7900-794-5
*1001 $aHurd, Yasmin L.
*24510$aIn vivo brain pharmacology of cocaine, amphetamine and related drugs :$ba microdialysis study
*260  $aStockholm,$c1989$y1989
*300  $a68 s.
*500  $aDiss. (sammanfattning) Stockholm : Karol. inst. - Härtill 8 uppsatser
*520  $aDopamine neurotransmission. In vivo analytical tools to monitor on-going neurochemical events. Scope and aim of the investigation. Animals. Analytical measurement of extracellular brain dopamine and acethylcholine. In vivo analytical measurement of cocaine concentrations. Statistical treatment of data. Methodological considerations. General features of microdialysis. Effects of perfusion media on extracellular levels of dopamine and its metabolites. Effects of anaesthesia on neurotransmission. Evaluation of neurotransmission differences between right and left caudateputamen. Characteristcs of dopamine uptake inhibitors. Pharmacokinetic property of dopamine transport inhibitors and dopamine overflow. In vivo assessment of dopamine metabolism. Evaluation of dopamine involvment in psychomotor stimulant reinforcement: models of addiction.
*650 4$aCocaine
*650 4$aAmphetamines
*650 4$aBrain chemistry
*650 4$aDopamine
*650 4$aNeuroregulators
*650 4$aAnimal
*653  $aKokain
*653  $aAmfetamin
*653  $aNeurokemiska aspekter
*7101 $aKarolinska institutet$0236620
*852  $hDiss.98
^