CAN:s bibliotek

*000      am
*00113132
*008070120|2006|||||||||||e||||||||||0|eng|d
*020  $a0-87969-753-9 (hardcover)$x0-87969-753-9
*24514$aThe cell biology of addiction$wcell biology of addiction
*260  $aCold Spring Harbor, N.Y,$cCold Spring Harbor Laboratory Press, cop 2006$y2006
*300  $ax, 465 s :$bill.
*520  $aAddiction genetics and genomics. Catechol-O-methyltransferase genotype, intermediate phenotype, and psychiatric disorders. Identifying genes affecting addiction risk in animal models. Endorphins, gene polymorphisms, stress responsivity, and special addiction: selected topics. Imaging the addicted brain. Neurotoxic effects of drugs of abuse: imaging and mechanisms. Development of the midbrain dopaminergic pathways. Transporter structure and function. Neuronal nicotinic acetylcholine receptors and nicotine dependence. Opioids as a model for cell biological studies of addictive drug action. Receptor-receptor interactions modulate opioid receptor function. The endocannabinoid system: from cell biology to therapy. Cocaine neurobiology: from targets to treatment. The oligomerization of G-protein-coupled receptors. The critical role of adenosine A2a receptors and Gi [beta-gamma] subunits in alcoholism and addiction: from cell biology to behavior. Neurotransmitter transporters: mechanisms and function. Synaptic vesicle trafficking and drug addiction in synapsin triple knockout mice. Synaptic plasticity in the mesolimbic dopamine system and addiction. Long-term memory storage in aplysia. Molecular mechanisms of drug addiction. Dynamic analyses of neural representations using the state-space modeling paradigm. Quantitative functional genomics and proteomics of drug abuse. (From the table of contents)
*650 4$aSubstance-related disorders
*650 4$aEtiology
*650 4$aBrain
*650 4$aPsychotropic drugs
*650 4$aMetabolism
*650 4$aPharmacokinetics
*653  $aDrogmissbruk
*653  $aEtiologi
*653  $aHjärnan
*653  $aMetabolism
*653  $aFarmakokinetik
*653  $aPsykofarmaka
*7001 $aMadras, Bertha K.$eed.
*852  $h4a140
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