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Titel och upphov Benzodiazepine and opioid dependence : clinical and meta-analytical studies
Utgivning, distribution etc. Lund University, Faculty of Medicine, Lund : 2006
Fysisk beskrivning
Serietitel - biuppslagsform Lund University, Faculty of Medicine Doctoral dissertation series, ISSN 1652-8220 ; 2006:74
Anmärkning: Innehållsbeskrivning, sammanfattning In the BZD (benzodiazepine) taper study (Paper l) 21 BZD dependent (DSM-lV) patients were included for a 10-day inpatient detoxification. In the dependence rate study (Paper ll) the frequency of prescribed drug dependence among 130 alcohol dependent patients in open care, 23 long-term institutionalized alcoholics, and 120 healthy controls were analysed. Common for the third and forth paper was the meta-analytical technique. In the methadone study (Paper lll) 8 RCT (randomised controlled trial) were included with 1,511 patients. In the naltrexon e review (Paper lV) 15 RCT were included with 990 patients. In the methadone study retention in treatment was higher (d=0.90), and opioid abuse and criminality was lower (d=0.61) and (d=0.35) respectively compared to controlled conditions. In the naltrexon e review naltrexon e was significantly better than controlled conditions in reducing the number of opioid positive urines (d=0.44). (From the abstract)
Term
Indexterm - Okontrollerad
ISBN
*000 am
*00113114
*008070120s2006||||sw|||||e|m||||||||0|eng|d
*020 $a91-85481-99-8
*1001 $aJohansson, Björn Axel,$d1959-
*24510$aBenzodiazepine and opioid dependence :$bclinical and meta-analytical studies / $cBjörn Axel Johansson
*260 $aLund :$bLund University, Faculty of Medicine,$c2006
*300 $a69 s :$bill.
*440 $aLund University, Faculty of Medicine Doctoral dissertation series,$x1652-8220 ;$v2006:74
*520 $aIn the BZD (benzodiazepine) taper study (Paper l) 21 BZD dependent (DSM-lV) patients were included for a 10-day inpatient detoxification. In the dependence rate study (Paper ll) the frequency of prescribed drug dependence among 130 alcohol dependent patients in open care, 23 long-term institutionalized alcoholics, and 120 healthy controls were analysed. Common for the third and forth paper was the meta-analytical technique. In the methadone study (Paper lll) 8 RCT (randomised controlled trial) were included with 1,511 patients. In the naltrexon e review (Paper lV) 15 RCT were included with 990 patients. In the methadone study retention in treatment was higher (d=0.90), and opioid abuse and criminality was lower (d=0.61) and (d=0.35) respectively compared to controlled conditions. In the naltrexon e review naltrexon e was significantly better than controlled conditions in reducing the number of opioid positive urines (d=0.44). (From the abstract)
*650 4$aOpioid-related disorders
*650 4$aBenzodiazepines
*650 4$aMeta-analysis
*650 4$aMethadone
*650 4$aNaltrexon e
*653 $aOpiatmissbruk
*653 $aBensodiazepiner
*852 $hDiss.373
*8564 $uhttps://lucris.lub.lu.se/ws/files/4438298/546759.pdf$zFulltext
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