CAN:s bibliotek

*00001198cam a22003377a 4500
*00125500
*00520070209164734.0
*008070122s2007    sw a     m    000 0 eng c
*020  $a91-7357-064-8$x91-7357-064-8
*020  $a978-91-7357-064-0$x978-91-7357-064-0
*035  $a(SE-LIBR)10323947
*1001 $aEllgren, Maria,$d1976-
*24510$aNeurobiological effects of early life cannabis exposure in relation to the gateway hypothesis /$cMaria Ellgren
*260  $aStockholm,$c2007$y2007
*300  $a56 s :$bdiagr.
*500  $aHärtill 4 uppsatser
*502  $aDiss. (sammanfattning) Stockholm : Karolinska institutet, 2007
*520  $aThe use of cannabis sativa preparations, such as hashish and marijuana, is wide-spred among young people, including pregnant women. Despite this concern, the consequences of cannabis exposure on brain during periods of active brain development, such as the prenatl phase and adolescense, is not well known. Several epidemiological studies support the cannabis gateway hypothesis, where early cannabis use is suggested to icrease the risk of initiating use of other illict drugs, e.g., amphetamine or heroine. However, the nature of such direct links are unclear. Therefore, the aim of this thesis was to test experimentally the cannabis gateway hypothesis, e.g., to determine wheather cannabis exposure during periods of active brain development alters reward-related behavior and neurobiology for psychostimulant and opioid drugs by the use of animal models. (From the abstract)
*650 4$aNucleus accumbens
*650 4$aCannabinoids
*650 4$aAmphetamine
*650 4$aDopamine
*650 4$aAdolescent behavior
*650 4$aCritical period (psychology)
*650 4$aPrenatal exposure delayed effects
*650 4$aOpioid-related disorders
*650 4$aPharmacology
*653  $aUngdomsbeteende
*653  $aCannabinoider
*653  $aAmfetamin
*653  $aDopamin
*653  $aNarkotikamissbruk
*653  $aKritisk period (psykologi)
*852  $hDiss.379
*8564 $uhttp://diss.kib.ki.se/2007/978-91-7357-064-0$zFulltext$galias: URL
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