CAN:s bibliotek

*000      am
*00119722
*008070120|1989|||||||||||e||||||||||0|eng|d
*020  $a0-8493-4521-9 (Vol. 1)
*020  $a0-8493-4522-7 (Vol. 2)
*020  $a0-8493-4523-5 (Vol. 3)
*24510$aHuman metabolism of alcohol /$ceditors Kathryn E. Crow, Richard D. Batt
*260  $aBoca Raton, Fla :$bCRC Press,$ccop. 1989$y1989
*300  $a3 vol.
*500  $aVol. 1 : Pharmacokinetics, medicolegal aspects, and general interests.  Vol. 2 : Regulation, enzymology, and metabolites of ethanol. Vol. 3 : Metabolic and physiological effects of alcohol
*520  $aVol. 1. Absorption, distribution, and elimination of alcohol. Pharmacokinetics of alcohol. Circadian variation in rates of ethanol metabolism. Total body water and blood alcohol levels: updating the fundamentals. Alcohol pharmacokinetics and forensic issues. Measurement of alcohol in blood and breath for legal purposes. Effects of low to moderate doses of ethanol on human driving-related performance. Alcohol as a teratogen: a teratological perspective of the fetal alcohol syndrome . Effectiveness of aversion therapy using disulfiram and related compounds. The genetics of alcoholism. Nutritional aspects of alcohol. Vol. 2. Regulation of rates of ethanol metabolism. The swift increase in alcohol metabolism (SIAM): a commentary on the regulation of alcohol metabolism in mammals. Hormonal regulation of alcohol dehydrogenase activity. Alcohol dehydrogenases - structure. Genetic polymorphism of human liver alcohol dehydrogenase and kinetic properties of the isoenzymes. Aldehyde dehydrogenases - structure. Aldehyde dehydrogenases - kinetic characterization. Cellular and intracellular distribution of aldehyde dehydrogenases. Reactions of aldehyde dehydrogenase with disulfiram and related compounds. Minor pathways of ethanol metabolism. Role of alcohol and aldehyde dehydrogenase in vivo: speculations on their natural substrates. Measurement of acetaldehyde and ethanol in blood, breath, and other biological material for experimental purposes. Human blood acetaldehyde. The role of acetaldehyde in alcohol addiction. Disulfiram-ethanol and related reactions. The flushing syndrome in Orientals. Production of 2,3-butanediol and 1,2-propanediol in severe alcoholics. Vol. 3. Metabolic effects of alcohol on the liver . Structural changes in liver caused by ethanol. Effects of ethanol and its metabolism on the brain . Effects of ethanol and its metabolites on the heart . Ethanol and the flow properties of blood. Alcohol interactions with the reproductive system. Interactions of ethanol and lipid metabolism. Interactions of ethanol and carbohydrate metabolism. Hepatic glutathione metabolism: alterations induced by alcohol consumption. Interactions of ethanol and drug metabolism. Effects of ethanol on membranes and their associated functions. Tolerance to alcohol and its relationship to dependence. Effects of ethanol on autonomic function. Effects of ethanol on vasopressin, thirst , and water balance.
*650 4$aMetabolism
*650 4$aPharmacokinetics
*650 4$aForensic medicine
*650 4$aBlood
*650 4$aBreath tests
*650 4$aAlcohol, ethyl
*650 4$aAutomobile driving
*650 4$aAlcohol drinking
*650 4$aTeratogens
*650 4$aDisulfiram
*650 4$aRehabilitation
*650 4$aGenetics
*650 4$aNutrition
*650 4$aAlcohol dehydrogenase
*650 4$aAldehyde dehydrogenase
*650 4$aAcetaldehyde
*650 4$aReproduction
*650 4$aLipids
*650 4$aCarbohydrates
*650 4$aDrugs
*650 4$aVasopressins
*650 4$aDrug interactions
*653  $aRättsmedicin
*653  $aBlodalkohol
*653  $aUtandningsprov
*653  $aAlkohol
*653  $aAlkoholkonsumtion
*653  $aBehandling
*653  $aAntabus
*653  $aÄrftlighet
*653  $aFetalt alkoholsyndrom
*7001 $aCrow, Kathryn E.$4edt
*7001 $aBatt, Richard D.$4edt
*852  $h4b66:1-3
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