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Cardiovascular toxicity of cocaine : underlying mechanisms
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  • Cardiovascular toxicity of cocaine : underlying mechanisms
Utgivning, distribution etc.
  • National Institute on Drug Abuse, Rockville, Md : 1991
Fysisk beskrivning
  • 238 s : ill.
Serietitel - biuppslagsform
  • NIDA research monograph series ; 108 DHHS publication ; 91-1767
Anmärkning: Allmän
  • E-bok
Anmärkning: Innehållsbeskrivning, sammanfattning
  • Maternal-fetal cardiovascular system: a target of cocaine. Pharmacokinetics and time-action profile of cocaine in dogs. Acute tolerance to the chronotropic effect of cocaine in humans. Mechanisms of cardiac and vascular responses to cocaine. Cardiovascular effects of cocaine in squirrel monkeys. Role of the sympathetic nervous system in the cardiovascular effects of cocaine. Cocaine-induced myocardial depression. Prevalence of myocardial depression. Prevalence of myocardial ischemia in cocaine addicts. Cocaine-induced myocardial infarction: clinical observations and pathogenetic considerations. Cardiac electrophysiological effects of cocaine in animal models. Effects of cocaine on intracellular calcium handling in cardiac and vascular smooth muscle. Cocaine-induced changes in the biochemistry and morphology of rabbit aorta. Effects of cocaine on the physiology of exercise. Effect of acute cocaine administration on cardiac and respiratory patterning in the freely moving cat. Direct and indirect morphological markers of cocaine toxicity in the human heart. Cocaine-associated cardiovascular disease: clinical and pathological aspects.
Term
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Personnamn
Institutionsnamn
  • National Institute on Drug Abuse
*000      am a        a
*00118558
*007cr |||||||||||
*008070120s1991||||xxu||||es|||||||||1|eng||
*24510$aCardiovascular toxicity of cocaine :$bunderlying mechanisms
*260  $aRockville, Md :$bNational Institute on Drug Abuse,$c1991
*300  $a238 s :$bill.
*440  $aNIDA research monograph series ;$v108 DHHS publication ; 91-1767
*500  $aE-bok
*520  $aMaternal-fetal cardiovascular system: a target of cocaine. Pharmacokinetics and time-action profile of cocaine in dogs. Acute tolerance to the chronotropic effect of cocaine in humans. Mechanisms of cardiac and vascular responses to cocaine. Cardiovascular effects of cocaine in squirrel monkeys. Role of the sympathetic nervous system in the cardiovascular effects of cocaine. Cocaine-induced myocardial depression. Prevalence of myocardial depression. Prevalence of myocardial ischemia in cocaine addicts. Cocaine-induced myocardial infarction: clinical observations and pathogenetic considerations. Cardiac electrophysiological effects of cocaine in animal models. Effects of cocaine on intracellular calcium handling in cardiac and vascular smooth muscle. Cocaine-induced changes in the biochemistry and morphology of rabbit aorta. Effects of cocaine on the physiology of exercise. Effect of acute cocaine administration on cardiac and respiratory patterning in the freely moving cat. Direct and indirect morphological markers of cocaine toxicity in the human heart. Cocaine-associated cardiovascular disease: clinical and pathological aspects.
*650 4$aCocaine
*650 4$aAnimal
*650 4$aCardiovascular system
*650 4$aNarcotic dependence
*650 4$aMyocardial infarction
*650 4$aCardiovascular diseases
*650 4$aSubstance use disorders
*653  $aKokain
*653  $aNarkomani
*653  $aDjurförsök
*653  $aSjukdom
*653  $aHjärtat
*653  $aMedicinska skadeverkningar
*7001 $aThadani, Pushpa$eed.
*7101 $aNational Institute on Drug Abuse$0124050
*85640$uhttps://archives.drugabuse.gov/sites/default/files/monograph108.pdf
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