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Titel och upphov Short chain dehydrogenases : structural characterization, family assignment and properties of prostaglandin and steroid dehydrogenases
Utgivning, distribution etc.
Fysisk beskrivning
Anmärkning: Allmän Diss. (sammanfattning) Stockholm : Karol. inst. - Härtill 6 uppsatser
Anmärkning: Innehållsbeskrivning, sammanfattning At the time this study was initiated three enzymes were known to be members of the short-chain dehydrogenase family: Drosphilia alcohol dehydrogenase, Bacillus glucose dehydrogenase and Klebsiella ribitol dehydrogenase. It was believed that enzymes involved in prostaglandin and steroid metabolism also could belong to this group. 15-hydroxyprostaglandin dehydrogenase was therefore purified from human placenta and the primary structures of that enzyme and a bacterial 3 alpha/20 beta-hydroxyst dehydrogenase were determined and indeed shown to be homologous to the short-chaindehydrogenases. During this work, several related sequences were reported and the enzyme family grew rapidly.
Term
Indexterm - Okontrollerad
ISBN
*000 am
*00117638
*008070120|1993|||||||||||e|m||||||||0|eng|d
*020 $a91-628-0939-3$x91-628-0939-3
*1001 $aKrook, Maria
*24510$aShort chain dehydrogenases :$bstructural characterization, family assignment and properties of prostaglandin and steroid dehydrogenases
*260 $aStockholm,$c1993$y1993
*300 $a71 s :$bill.
*500 $aDiss. (sammanfattning) Stockholm : Karol. inst. - Härtill 6 uppsatser
*520 $aAt the time this study was initiated three enzymes were known to be members of the short-chain dehydrogenase family: Drosphilia alcohol dehydrogenase, Bacillus glucose dehydrogenase and Klebsiella ribitol dehydrogenase. It was believed that enzymes involved in prostaglandin and steroid metabolism also could belong to this group. 15-hydroxyprostaglandin dehydrogenase was therefore purified from human placenta and the primary structures of that enzyme and a bacterial 3 alpha/20 beta-hydroxyst dehydrogenase were determined and indeed shown to be homologous to the short-chaindehydrogenases. During this work, several related sequences were reported and the enzyme family grew rapidly.
*650 4$aProstaglandins
*650 4$aEnzymes
*650 4$aAlcohol dehydrogenase
*650 4$aHydroxyprostaglandin dehydrogenases
*650 4$aNADH dehydrogenase
*650 4$aHydroxysteroid dehydrogenases
*653 $aAlkoholdehydrogenas
*852 $hDiss.175
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