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Medications development : drug discovery, databases, and computer-aided drug design
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  • Medications development : drug discovery, databases, and computer-aided drug design
Utgivning, distribution etc.
  • National Institute on Drug Abuse, Rockville, Md : 1993
Fysisk beskrivning
  • 288 s : ill.
Serietitel - biuppslagsform
  • NIDA research monograph series ; 134 NIH publication ; 93-3638
Anmärkning: Allmän
  • Based on the papers and discussions from a technical review ... held on November 14-16, 1991
Anmärkning: Innehållsbeskrivning, sammanfattning
  • Synthetic peptide combinatorial libraries may be used to determine peptide ligands for opioid receptors. Toward the design of new inhibitors: a computer modeling approach. Use of computer graphics in drug design. Purification and cloning of opioid receptors. The pharmacophore for opioid activity. The molecular basis of opioid potency and selectivity. Molecular determinants of cannabinoid activity. Cocaine receptor. The use of conformational restriction and molecular modeling techniques in the development of receptor-specific opioid peptide agonists and antagonists. Probes for the cannabinoid sites of action.
Term
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Personnamn
Institutionsnamn
  • National Institute on Drug Abuse
*000      am a        a
*00117242
*007cr |||||||||||
*008070120s1993||||xxu||||es|||||||||1|eng||
*24510$aMedications development :$bdrug discovery, databases, and computer-aided drug design
*260  $aRockville, Md :$bNational Institute on Drug Abuse,$c1993
*300  $a288 s :$bill.
*440  $aNIDA research monograph series ;$v134 NIH publication ; 93-3638
*500  $aBased on the papers and discussions from a technical review ... held on November 14-16, 1991
*520  $aSynthetic peptide combinatorial libraries may be used to determine peptide ligands for opioid receptors. Toward the design of new inhibitors: a computer modeling approach. Use of computer graphics in drug design. Purification and cloning of opioid receptors. The pharmacophore for opioid activity. The molecular basis of opioid potency and selectivity. Molecular determinants of cannabinoid activity. Cocaine receptor. The use of conformational restriction and molecular modeling techniques in the development of receptor-specific opioid peptide agonists and antagonists. Probes for the cannabinoid sites of action.
*650 4$aDrug design
*650 4$aReceptors, opioid
*650 4$aInformation systems
*650 4$aComputer-aided design
*650 4$aCannabinoids
*650 4$aNarcotics
*650 4$aDrugs
*653  $aDatabaser
*653  $aLäkemedel
*653  $aReceptorer
*653  $aFarmakologi
*7001 $aRapaka, Rao S.$eed.
*7001 $aHawks, Richard L.$eed.
*7101 $aNational Institute on Drug Abuse$0124050
*85640$uhttps://archives.drugabuse.gov/sites/default/files/monograph134.pdf
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