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Imaging techniques in medications development : preclinical and clinical aspects
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  • Imaging techniques in medications development : preclinical and clinical aspects
Utgivning, distribution etc.
  • National Institute on Drug Abuse, Rockville, Md : 1994
Fysisk beskrivning
  • 193 s : ill.
Serietitel - biuppslagsform
  • NIDA research monograph series ; 138 NIH publication ; 94-3728
Anmärkning: Allmän
  • E-bok
Anmärkning: Innehållsbeskrivning, sammanfattning
  • PET, SPECT, and probes in drug design and development. Positron emission tomography in studies of drug abuse. Imaging brain function in animals to understand drugs of abuse and potential pharmacotherapies. Brain-imaging studies of the combined use of cocaine and alcohol and of the pharmacokinetics of cocaethylene. Positron emission tomography of cocaine binding sites on the dopamine transporter. Metabolic mapping methods for the identification of the neural substrates of the effects of novel tropane analogs. Noninvasive evaluation of the sympathetic nervous system of the heart by nuclear imaging procedures. Development of PET/SPECT ligands for the serotonin transporter. SPECT imaging of dopamine and serotonin transporters in nonhuman primate brain. Cerebral blood flow changes with acute cocaine intoxication: clinical correlations with SPECT, CT, and MRI. An introduction to magnetic resonance methods for clinical research.
Term
Indexterm - Okontrollerad
Personnamn
Institutionsnamn
  • National Institute on Drug Abuse 
*000      am a        a
*00117087
*007cr |||||||||||
*008070120s1994||||xxu||||es|||||||||1|eng||
*24510$aImaging techniques in medications development :$bpreclinical and clinical aspects
*260  $aRockville, Md :$bNational Institute on Drug Abuse,$c1994
*300  $a193 s :$bill.
*440  $aNIDA research monograph series ;$v138 NIH publication ; 94-3728
*500  $aE-bok
*520  $aPET, SPECT, and probes in drug design and development. Positron emission tomography in studies of drug abuse. Imaging brain function in animals to understand drugs of abuse and potential pharmacotherapies. Brain-imaging studies of the combined use of cocaine and alcohol and of the pharmacokinetics of cocaethylene. Positron emission tomography of cocaine binding sites on the dopamine transporter. Metabolic mapping methods for the identification of the neural substrates of the effects of novel tropane analogs. Noninvasive evaluation of the sympathetic nervous system of the heart by nuclear imaging procedures. Development of PET/SPECT ligands for the serotonin transporter. SPECT imaging of dopamine and serotonin transporters in nonhuman primate brain. Cerebral blood flow changes with acute cocaine intoxication: clinical correlations with SPECT, CT, and MRI. An introduction to magnetic resonance methods for clinical research.
*650 4$aTomography, emission-computed, single-photon
*650 4$aReceptors, dopamine
*650 4$aRadiography
*650 4$aSubstance abuse
*650 4$aNarcotics
*650 4$aCocaine
*650 4$aAlcohol, ethyl
*650 4$aTomography, emission-computed
*653  $aReceptorer
*653  $aDrogmissbruk
*653  $aNarkotika
*653  $aKokain
*653  $aAlkohol
*7001 $aSorer, Heinz$eed.
*7001 $aRapaka, Rao S.$eed.
*7101 $aNational Institute on Drug Abuse$0124050
*85640$uhttps://archives.drugabuse.gov/sites/default/files/monograph138.pdf
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