CAN:s bibliotek

*000      am
*00116694
*008070120|1997|||||||||||e|m||||||||0|eng|d
*020  $a951-42-4610-1$x951-42-4610-1
*1001 $aEkman, Ann-Charlotte
*24514$aThe acute effects of evening-ingested ethanol on human nocturnal endocrine regulation systems$wacute effects of evening-ingested ethanol on human nocturnal endocrine regulation systems
*260  $aOulu,$c1997$y1997
*300  $a56 s.
*440 0$aActa universitatis Ouluensis. Series D Medica ;$v416
*500  $aDiss. (sammanfattning) Oulu : Yliap.
*520  $aThe task of this study was to assess some of the perhaps most central endocrine effects of moderate ethanol intake in volunteers. To this end, a randomized, double blind, cross-over study design was set up with nine healthy volunteers consuming 0, 0.5 and 1.0 grams of ethanol/kg body weight (kg bw) with one-week intervals. After this series of experiments a TRH stimulation test was carried out with six healthy vounteers using ethanol doses of 0 and 1.0 g/kg bw. In conclusion, ethanol intake was found to cause several significant changes in human nocturnal endocrinology, especially in the secretion of melatonin (MT), noradrenaline (NA), growth hormone (GH), thyrotropin (TSH), insulin and insulin-like growth factor binding protein-1 (IGFBP-1). The ethanol-induced changes in nocturnal hormone secretion observed in these experiments evidently indicate a cause-effect relationship to the brain mechanisms monitoring sleep, bodily rhythms, stress reactions and metabolism.
*650 4$aInsulin-like growth-factor binding protein 1
*650 4$aEndocrinology
*650 4$aAlcohol, ethyl
*650 4$aMale
*650 4$aFemale
*650 4$aAdult
*650 4$aSleep
*650 4$aStress
*650 4$aMelatonin
*650 4$aAtrial natiuretic factor
*650 4$aPituitary hormones
*650 4$aWater-electrolyte balance
*653  $aAlkohol
*653  $aHormoner
*653  $aFysiologi
*653  $aMetabolism
*653  $aSömn
*653  $aStress
*852  $hDiss.219
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