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Pharmacokinetics, metabolism, and pharmaceutics of drugs of abuse.
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  • Pharmacokinetics, metabolism, and pharmaceutics of drugs of abuse.
Utgivning, distribution etc.
  • National Institute on Drug Abuse, Rockville, Md : 1997
Fysisk beskrivning
  • 316 s : ill.
Serietitel - biuppslagsform
  • NIDA research monograph series ; 173
  • NIH publication ; 97-4141
Anmärkning: Allmän
  • E-bok
Anmärkning: Innehållsbeskrivning, sammanfattning
  • The potential role of the cytochrome P-450 2D6 pharmacogenetic polymorphism in drug abuse. Human liver cocaine carboxylesterases. Effects of ethanol on cocaine metabolism and disposition in the rat. Individual differences in nicotine kinetics and metabolism in humans. Inhibitors of anandamide breakdown. Metabolic bioactivation reactions potencially related to drug toxicities. The role of iminium-enamine species in the toxication and detoxication of cyclic tertiary amines. Neurotoxicity of amphetamines and their metabolites. Potential new insights into the molecular mechanisms of metamphetamine-induced neurodegeneration. Immunotoxicology of opioids, inhalants, and other drugs of abuse. Inhalation studies with drugs of abuse. Biocatalysts in detoxication of drugs of abuse. Antibodies as pharmacokinetic and metabolic modifiers of neurotoxicity. Toxikinetics in the national toxicology program. (From the table of contents)
Term
Indexterm - Okontrollerad
Personnamn
Institutionsnamn
  • National Institute on Drug Abuse 
*000      am
*00116665
*007cr
*008070120s1997||||xxu||||e||||||||||0|eng|d
*24510$aPharmacokinetics, metabolism, and pharmaceutics of drugs of abuse.
*260  $aRockville, Md :$bNational Institute on Drug Abuse,$c1997
*300  $a316 s :$bill.
*440  $aNIDA research monograph series ;$v173
*440  $aNIH publication ;$v97-4141
*500  $aE-bok
*520  $aThe potential role of the cytochrome P-450 2D6 pharmacogenetic polymorphism in drug abuse. Human liver cocaine carboxylesterases. Effects of ethanol on cocaine metabolism and disposition in the rat. Individual differences in nicotine kinetics and metabolism in humans. Inhibitors of anandamide breakdown. Metabolic bioactivation reactions potencially related to drug toxicities. The role of iminium-enamine species in the toxication and detoxication of cyclic tertiary amines. Neurotoxicity of amphetamines and their metabolites. Potential new insights into the molecular mechanisms of metamphetamine-induced neurodegeneration. Immunotoxicology of opioids, inhalants, and other drugs of abuse. Inhalation studies with drugs of abuse. Biocatalysts in detoxication of drugs of abuse. Antibodies as pharmacokinetic and metabolic modifiers of neurotoxicity. Toxikinetics in the national toxicology program. (From the table of contents)
*650 4$aPharmacokinetics
*650 4$aMetabolism
*650 4$aAnimal
*650 4$aCocaine
*650 4$aEthanol
*650 4$aNicotine
*650 4$aAmphetamines
*650 4$aSolvents
*650 4$aToxicology
*653  $aNarkotika
*653  $aAlkohol
*653  $aFarmakologi
*653  $aDjurförsök
*653  $aAmfetamin
*653  $aNikotin
*653  $aKokain
*7001 $aRapaka, Rao S.$eed. et al
*7101 $aNational Institute on Drug Abuse$0124050
*85640$uhttps://archives.drugabuse.gov/sites/default/files/monograph173_0.pdf
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